Hampton Plantation State Historic Site is home to the remote, final remnants of a colonial-era rice plantation. The plantation now serves as an interpretive site for the system of slavery and rice cultivation in the region from the colonial period through the end of the Civil War. The property also tells the story of the freed people who made their homes in the Santee Delta region for generations after emancipation.

Visitors can explore the mansion to learn how it was constructed and changed over time from the early 18th century. The kitchen building and the unearthed foundation of one of the slave dwellings show the disparity between the lifestyles of the planters and the enslaved.

The plantation grounds include walking trails through pine forest, views of Wambaw Creek, and the remains of rice fields that once stretched as far as the eye could see. Hampton inspired the works of South Carolinas first poet laureate, Archibald Rutledgethe last private owner of the house, who lived there until 1969. The site is a National Historic Landmark.